Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 13/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500846 | 0.88 | CYBB (0.53) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500854 | 0.87 | CYBB (0.52) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500852 | 0.85 | CYBB (0.46) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500829 | 0.83 | CYBB (0.52) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500853 | 0.77 | CYBB (0.68) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500782 | 0.77 | CYBB (0.58) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501065 | 0.76 | PIM1 (0.59) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501364 | 0.76 | SLC2A1 (0.63) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500763 | 0.75 | CYBB (0.57) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500755 | 0.74 | CYBB (0.73) | CYBBSLC2A1PIM1PIM2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |