Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 7/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 8/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500789 | 0.84 | CYBB (0.68) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500791 | 0.82 | CYBB (0.70) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13501227 | 0.81 | CYBB (0.69) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500843 | 0.81 | CYBB (0.69) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500788 | 0.80 | CYBB (0.68) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500793 | 0.80 | CYBB (0.71) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500792 | 0.79 | CYBB (0.65) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500841 | 0.79 | CYBB (0.65) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500840 | 0.79 | CYBB (0.65) | CYBBSLC2A1JAK2CYP3A4PIM1 | |
| SCHEMBL13500817 | 0.79 | SLC2A1 (0.65) | CYBBSLC2A1JAK2CYP3A4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |