Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | CYBB | P04839 | 2/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501162 | 0.97 | SLC2A1 (0.59) | SLC2A1CYBBSIRT2SIRT1SIRT3 | |
| SCHEMBL13501329 | 0.93 | SLC2A1 (0.62) | SLC2A1CYBBSIRT2SIRT1SIRT3 | |
| SCHEMBL13501057 | 0.92 | SLC2A1 (0.49) | SLC2A1CYBBSIRT2SIRT1SIRT3 | |
| SCHEMBL13501293 | 0.92 | SLC2A1 (0.66) | SLC2A1CYBBSIRT2SIRT1SIRT3 | |
| SCHEMBL13501352 | 0.91 | MAPT (0.49) | SLC2A1CYBBLRRK2PIM1PIM2 | |
| SCHEMBL13501058 | 0.91 | MAPK14 (0.51) | SLC2A1CYBBSIRT2SIRT1SIRT3 | |
| SCHEMBL13501123 | 0.90 | SLC2A1 (0.47) | SLC2A1CYBBLRRK2PIM1PIM2 | |
| SCHEMBL13501104 | 0.90 | SLC2A1 (0.63) | SLC2A1CYBBLRRK2PIM1PIM2 | |
| SCHEMBL13501137 | 0.90 | SLC2A1 (0.47) | SLC2A1CYBBSIRT2LRRK2PRMT5 | |
| SCHEMBL13501088 | 0.89 | SLC2A1 (0.57) | SLC2A1CYBBSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |