Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.80 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 12/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501275 | 0.93 | CYBB (0.78) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501279 | 0.93 | CYBB (0.78) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13500863 | 0.91 | CYBB (0.84) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501214 | 0.91 | CYBB (0.78) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501140 | 0.91 | CYBB (0.86) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501274 | 0.89 | CYBB (0.83) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501174 | 0.89 | CYBB (0.76) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501176 | 0.89 | CYBB (0.76) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501190 | 0.89 | CYBB (0.76) | CYBBSLC2A1PIM1PIM2FLT3 | |
| SCHEMBL13501312 | 0.89 | CYBB (1.00) | CYBBSLC2A1PIM1PIM2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |