Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SF3B3 | Q15393 | 8/20 | 0.51 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396509 | 0.96 | SF3B3 (0.48) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14423036 | 0.93 | SF3B3 (0.50) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13503191 | 0.91 | SF3B3 (0.46) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14396197 | 0.91 | SF3B3 (0.55) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22062173 | 0.89 | SF3B3 (0.43) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22062185 | 0.89 | SF3B3 (0.43) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL371282 | 0.87 | SF3B3 (0.69) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24959846 | 0.86 | SF3B3 (0.44) | SF3B3HMGCRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18672301 | 0.86 | SF3B3 (0.49) | SF3B3 | |
| SCHEMBL12394079 | 0.83 | SF3B3 (0.48) | SF3B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7667052-B2 | Bioactive substance | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-7667052-B2 | Bioactive substance | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |