SCHEMBL13503231

SCHEMBL13503231

CCNC(=O)OC1/C=C/C(C)C(/C(C)=C/C=C/C(C)CC2OC2C(C)C(C)CC)OC(=O)CC(C)CCC1(C)C

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 10/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13701255 0.95 SF3B3 (0.52) SF3B3
SCHEMBL13503222 0.93 SF3B3 (0.55) SF3B3
SCHEMBL13503230 0.92 SF3B3 (0.51) SF3B3
SCHEMBL13701256 0.91 SF3B3 (0.50) SF3B3
SCHEMBL13503224 0.91 SF3B3 (0.50) SF3B3
SCHEMBL13503226 0.89 SF3B3 (0.48) SF3B3
SCHEMBL13503211 0.87 SF3B3 (0.62) SF3B3
SCHEMBL13503225 0.87 SF3B3 (0.47) SF3B3
SCHEMBL13503223 0.87 SF3B3 (0.57) SF3B3
SCHEMBL13715210 0.86 SF3B3 (0.55) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7667052-B2 Bioactive substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-23 US disclosed