SCHEMBL13503233

SCHEMBL13503233

CC/C(=N\OC)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)/C=C/C1C

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 10/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3552260 1.00 SF3B3 (0.63) SF3B3
SCHEMBL1505052 0.91 SF3B3 (0.76) SF3B3
SCHEMBL13503234 0.91 SF3B3 (0.58) SF3B3
SCHEMBL1505060 0.91 SF3B3 (0.58) SF3B3
SCHEMBL3625340 0.88 SF3B3 (0.64) SF3B3
SCHEMBL1505007 0.87 SF3B3 (0.67) SF3B3
SCHEMBL3619306 0.87 SF3B3 (0.66) SF3B3
SCHEMBL12877318 0.86 SF3B3 (0.76) SF3B3
SCHEMBL12877481 0.86 SF3B3 (0.76) SF3B3
SCHEMBL14539614 0.86 SF3B3 (0.76) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7667052-B2 Bioactive substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-23 US disclosed
US-7667052-B2 Bioactive substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-23 US disclosed