Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504193 | 0.94 | SCN3A (0.38) | SCN3APTGER3SCN5ASCN9ASLC6A9 | |
| SCHEMBL15104179 | 0.87 | SCN3A (0.36) | SCN3APTGER3SCN5ASCN9ANAMPT | |
| SCHEMBL15104129 | 0.87 | SCN3A (0.38) | SCN3APTGER3SCN5ASCN9ANAMPT | |
| SCHEMBL2660829 | 0.83 | GCK (0.38) | SCN3APTGER3SCN5ASCN9APTGER4 | |
| SCHEMBL2661832 | 0.81 | PTGER3 (0.38) | PTGER3PTGER4MEN1ALDH1A1KMT2A | |
| SCHEMBL13053299 | 0.81 | SCN3A (0.40) | SCN3ASCN5ASCN9AMEN1HPGD | |
| SCHEMBL3756320 | 0.80 | NPC1 (0.35) | PTGER3MEN1ALDH1A1HPGDTSHR | |
| SCHEMBL3756302 | 0.78 | GCK (0.39) | SCN3APTGER3SCN5ASCN9AALDH1A1 | |
| SCHEMBL2661013 | 0.75 | GRM4 (0.36) | SCN3APTGER3MEN1ALDH1A1HPGD | |
| SCHEMBL15104304 | 0.74 | PTGER3 (0.34) | SCN3APTGER3SCN9ANAMPTSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299115-B2 | Pyrrole-2-carboxamide derivatives as glucokinase activators, their process and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2012-10-30 | — | — | US | disclosed |