Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359549 | 1.00 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL1129603 | 0.91 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL1129601 | 0.91 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL4361718 | 0.91 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL4360605 | 0.91 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL4360602 | 0.91 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL4361713 | 0.91 | TNK2 (1.00) | TNK2IGF1R | |
| SCHEMBL13618371 | 0.89 | TNK2 (0.81) | TNK2IGF1R | |
| SCHEMBL13618405 | 0.88 | TNK2 (0.80) | TNK2IGF1R | |
| SCHEMBL4358974 | 0.88 | TNK2 (1.00) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481733-B2 | Substituted imidazopyr- and imidazotri-azines | OSI Pharmaceuticals, LLC (US) | 2013-07-09 | — | — | US | claimed |
| EP-2283020-B1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARM INC (US) | 2012-10-31 | — | — | EP | claimed |
| EP-2283020-B1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARM INC (US) | 2012-10-31 | — | — | EP | disclosed |