Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 15/20 | 0.37 |
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | PPARD | Q03181 | 5/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693308 | 1.00 | CMA1 (0.37) | CMA1PPARAPPARGPPARDPTGES | |
| SCHEMBL13508324 | 0.93 | PPARG (0.43) | CMA1PPARAPPARGPPARDPTGES | |
| SCHEMBL3687326 | 0.93 | PPARG (0.43) | CMA1PPARAPPARGPPARDPTGES | |
| SCHEMBL13509514 | 0.88 | CMA1 (0.40) | CMA1PPARAPPARGPPARDPTGES | |
| SCHEMBL3686749 | 0.77 | PPARG (0.43) | CMA1PPARAPPARGPPARD | |
| SCHEMBL3686996 | 0.76 | CMA1 (0.37) | CMA1PPARAPPARGPPARD | |
| SCHEMBL13508598 | 0.74 | CMA1 (0.43) | CMA1 | |
| SCHEMBL3684613 | 0.74 | PPARG (0.34) | CMA1PPARAPPARGPPARD | |
| SCHEMBL13509513 | 0.74 | CMA1 (0.36) | CMA1 | |
| SCHEMBL3689003 | 0.73 | CMA1 (0.42) | CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |