Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL3685478 | 0.98 | GAA (0.56) | GAANPSR1PPARAPPARGCYP4A11 | |
| SCHEMBL6375038 | 0.91 | CYP4F2 (0.66) | GAANPSR1PPARAPPARGCYP4A11 | |
| SCHEMBL11817150 | 0.89 | PPARA (0.63) | GAANPSR1PPARAPPARGKDM4E | |
| SCHEMBL12869146 | 0.88 | PPARA (0.69) | GAANPSR1PPARAPPARG | |
| SCHEMBL28405319 | 0.87 | PPARA (0.71) | GAANPSR1PPARAPPARGALDH1A1 | |
| SCHEMBL15922116 | 0.87 | PPARA (0.71) | GAANPSR1PPARAPPARGALDH1A1 | |
| SCHEMBL2292200 | 0.85 | PPARA (0.55) | GAANPSR1PPARAPPARGKDM4E | |
| Hydrochloric Acid SCHEMBL28797126 | 0.85 | GAA (0.55) | GAANPSR1PPARAPPARGKDM4E | |
| SCHEMBL1431250 | 0.84 | CYP4A11 (0.57) | PPARACYP4A11CYP4F2LTA4HEPHX2 | |
| SCHEMBL8321862 | 0.84 | GAA (0.64) | GAANPSR1PPARAPPARGCYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |