SCHEMBL13512643

SCHEMBL13512643

[N-]=[N+]=NC1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18513750 0.97 EPHX1 (0.39)
SCHEMBL16274551 0.97 EPHX1 (0.39)
SCHEMBL13906437 0.97 EPHX1 (0.39)
SCHEMBL14015255 0.97
SCHEMBL16804784 0.97 EPHX1 (0.39)
SCHEMBL16730684 0.97 EPHX1 (0.39)
SCHEMBL19185841 0.97 EPHX1 (0.39)
SCHEMBL15304150 0.97 EPHX1 (0.39)
Hydrochloric Acid SCHEMBL16637214 0.97
SCHEMBL13602972 0.97 EPHX1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5494827-A PRODUCES DIOXETANE DIONE INTERMEDIATE WHICH DECOMPOSES TO EMIT LIGHT AGENCY FOR DEFENSE DEVELOPMENT (KR) 1996-02-27 US claimed
CN-114105958-B Hydroximic acid-containing 2-phenylamino pyrimidine derivatives and application thereof 郑州大学第一附属医院 2022-11-22 CN disclosed
US-11267824-B2 Inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase IDORSIA PHARMACEUTICALS LTD (CH) 2022-03-08 US disclosed
CN-114105958-A Hydroximic acid-containing 2-phenylamino pyrimidine derivatives and application thereof 郑州大学第一附属医院 2022-03-01 CN disclosed
CN-113999210-A Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof 郑州大学第一附属医院 2022-02-01 CN disclosed
EP-3668880-B1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE IDORSIA PHARMACEUTICALS LTD (CH) 2021-10-06 EP disclosed
US-20200216467-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE IDORSIA PHARMACEUTICALS LTD (CH) 2020-07-09 US disclosed
EP-3668880-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE Idorsia Pharmaceuticals Ltd (CH) 2020-06-24 EP disclosed
CN-110997682-A Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase 爱杜西亚药品有限公司 2020-04-10 CN disclosed
US-10391082-B2 Protein kinase inhibitors ORION CORPORATION (FI) 2019-08-27 US disclosed
US-20120040964-A1 N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS INCYTE CORPORATION (US) 2012-02-16 US disclosed
US-8071624-B2 N-substituted piperidines and their use as pharmaceuticals INCYTE CORPORATION (US) 2011-12-06 US disclosed
WO-2011117145-A2 PYRROLOPYRAZINE KINASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2011-09-29 WO disclosed
US-20110230462-A1 Pyrrolopyrazine Kinase Inhibitors HENDRICKS ROBERT THAN 2011-09-22 US disclosed
EP-2319825-A1 ENZYMATIC SYNTHESIS OF ENANTIOMERICALLY ENRICHED DERIVATIVES OF CIS- AND TRANS-CYCLOPENTANE-1,2-DIAMINES EntreChem, S.L. (ES) 2011-05-11 EP disclosed
US-20100204280-A1 CINNAMOYL INHIBITORS OF TRANSGLUTAMINASE UNIVERSITE DE MONTREAL (CA) 2010-08-12 US disclosed
US-20100204280-A1 CINNAMOYL INHIBITORS OF TRANSGLUTAMINASE UNIVERSITE DE MONTREAL (CA) 2010-08-12 US disclosed
WO-2010007202-A1 ENZYMATIC SYNTHESIS OF ENANTIOMERICALLY ENRICHED DERIVATIVES OF CIS- AND TRANS-CYCLOPENTANE-1,2-DIAMINES ENTRECHEM, S.L. (ES) 2010-01-21 WO disclosed
WO-2009139863-A2 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY (US) 2009-11-19 WO disclosed
WO-2008144933-A1 CINNAMOYL INHIBITORS OF TRANSGLUTAMINASE Université de Montréal (CA) 2008-12-04 WO disclosed