Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268669 | 0.89 | MEN1 (0.36) | CHRM4KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL13611438 | 0.85 | FFAR1 (0.39) | FFAR1KMT2AFFAR4 | |
| SCHEMBL13611501 | 0.78 | FFAR1 (0.37) | FFAR1KMT2A | |
| SCHEMBL13513796 | 0.78 | FFAR1 (0.40) | FFAR1FFAR4 | |
| SCHEMBL13611496 | 0.77 | FFAR4 (0.36) | MEN1KMT2AFFAR4ALDH1A1 | |
| SCHEMBL13611611 | 0.77 | FFAR4 (0.42) | FFAR1FFAR4 | |
| SCHEMBL8268235 | 0.77 | FFAR4 (0.42) | FFAR1FFAR4 | |
| SCHEMBL8269829 | 0.75 | FFAR4 (0.34) | FFAR1FFAR4 | |
| SCHEMBL8268956 | 0.75 | GPBAR1 (0.38) | FFAR4 | |
| SCHEMBL8268228 | 0.74 | FFAR4 (0.39) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805141-B1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME (GB) | 2010-01-20 | — | — | EP | disclosed |