Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521861 | 0.90 | MAPT (0.50) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL349218 | 0.88 | CYP3A4 (0.46) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL1943002 | 0.87 | PTGDR2 (0.45) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL348830 | 0.87 | CYP3A4 (0.60) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL350502 | 0.87 | PTGDR2 (0.46) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL347736 | 0.86 | CYP3A4 (0.46) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL348266 | 0.86 | MAPT (0.47) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL347633 | 0.85 | CYP3A4 (0.46) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL13521864 | 0.84 | MAPT (0.48) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL349217 | 0.84 | PTGDR2 (0.49) | PTGDR2SMN1; SMN2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003127-A2 | ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |