Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216933 | 0.85 | CA1 (0.40) | CA1CA2ZDHHC7TAS1R3TAS1R1 | |
| SCHEMBL19414321 | 0.85 | CA1 (0.48) | CA1CA2ZDHHC7TAS1R3TAS1R1 | |
| SCHEMBL17449636 | 0.84 | CA1 (0.42) | CA1CA2ZDHHC7TAS1R3TAS1R1 | |
| SCHEMBL14420244 | 0.84 | CA1 (0.38) | CA1CA2ZDHHC7POLBACHE | |
| Hydrogen Sulfide SCHEMBL28218746 | 0.83 | CA1 (0.39) | CA1CA2ZDHHC7TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL28210945 | 0.83 | CA1 (0.39) | CA1CA2ZDHHC7TAS1R3TAS1R1 | |
| SCHEMBL12534429 | 0.80 | CA1 (0.33) | CA1CA2ZDHHC7POLBCHRNB2 | |
| SCHEMBL12534424 | 0.80 | CYP2C9 (0.48) | TAS1R3TAS1R1CYP2C9 | |
| Benzene SCHEMBL28167517 | 0.80 | POLB (0.44) | CA1CA2ZDHHC7TAS1R3TAS1R1 | |
| SCHEMBL12534428 | 0.80 | ANPEP (0.36) | CA1CA2ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004054-A2 | CONSTRUCTION OF CELL PENETRATING NUCLEIC ACIDS | NOVOSOM AG (DE) | 2010-01-14 | — | — | WO | disclosed |