Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523050 | 0.94 | MAPT (0.48) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13523065 | 0.92 | KDM4E (0.51) | PTGS2TP53MAPTTHRBAGPAT2 | |
| SCHEMBL13522838 | 0.92 | PPARG (0.54) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13522844 | 0.91 | PPARG (0.57) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13523019 | 0.91 | MAPT (0.48) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13523053 | 0.89 | MAPT (0.52) | PTGS2TP53MAPTTHRBAGPAT2 | |
| SCHEMBL13523068 | 0.89 | MAPT (0.46) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13523037 | 0.89 | PPARG (0.49) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13523048 | 0.88 | RXFP1 (0.47) | PTGS2PPARGPPARATP53MAPT | |
| SCHEMBL13523043 | 0.87 | MAPT (0.48) | PTGS2TP53MAPTTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |