Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | CNR1 | P21554 | 8/20 | 0.49 |
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523932 | 0.98 | ESR1 (0.48) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL13523933 | 0.92 | ESR1 (0.55) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL9506249 | 0.91 | MAPT (0.55) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL9504010 | 0.91 | MAPT (0.55) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL9505321 | 0.91 | MAPT (0.55) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL9503281 | 0.91 | MAPT (0.55) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL9506262 | 0.89 | MAPT (0.57) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL13523930 | 0.84 | ESR1 (0.52) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL13523938 | 0.84 | ESR1 (0.64) | CNR2CNR1ESR1ESR2MAPT | |
| SCHEMBL8540208 | 0.83 | MAPT (0.58) | ESR1ESR2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049599-B1 | BASIC BISAZO COMPOUNDS | ARCHROMA IP GMBH (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-8921564-B2 | Basic bisazo compounds | CLARIANT FINANCE (BVI) LTD. (VG) | 2014-12-30 | — | — | US | disclosed |
| US-8921564-B2 | Basic bisazo compounds | CLARIANT FINANCE (BVI) LTD. (VG) | 2014-12-30 | — | — | US | disclosed |
| US-20100000033-A1 | Basic Bisazo Compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-01-07 | — | — | US | disclosed |
| US-20100000033-A1 | Basic Bisazo Compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-01-07 | — | — | US | disclosed |
| WO-2008012322-A1 | BASIC BISAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-31 | — | — | WO | disclosed |