Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525555 | 1.00 | MEN1 (0.64) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13127867 | 0.88 | MEN1 (0.62) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1267675 | 0.85 | MEN1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL9137609 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL8783095 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL27405627 | 0.85 | MEN1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL30114493 | 0.85 | MEN1 (0.59) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2877536 | 0.85 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8498107 | 0.85 | SLC6A2 (0.61) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2877540 | 0.85 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649002-B2 | (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists | PFIZER INC (US) | 2010-01-19 | — | — | US | disclosed |
| US-7351711-B2 | Tricyclic indanyls as integrin inhibitors | JANSSEN PHARMACEUTICAL, N.V. (BE) | 2008-04-01 | — | — | US | disclosed |