Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.70 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525831 | 0.84 | S1PR1 (0.68) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13525847 | 0.84 | S1PR1 (0.67) | S1PR1S1PR3NR1H4NPC1RAB9A | |
| SCHEMBL13417276 | 0.83 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL13525830 | 0.81 | S1PR1 (0.70) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14327885 | 0.78 | S1PR1 (0.69) | S1PR1S1PR3NR1H4NPC1RAB9A | |
| SCHEMBL14327886 | 0.77 | S1PR1 (0.73) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13525827 | 0.75 | S1PR1 (0.70) | S1PR1S1PR3NR1H4NPC1RAB9A | |
| SCHEMBL14327860 | 0.74 | S1PR1 (0.59) | S1PR1S1PR3NR1H4NPC1RAB9A | |
| SCHEMBL13416322 | 0.74 | S1PR1 (1.00) | S1PR1S1PR3NPC1RAB9A | |
| SCHEMBL13417067 | 0.73 | S1PR1 (1.00) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010001-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010001-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR4 | S1PR1 1/4885S1PR3 2/4885NR1H4 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.