Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | CASP1 | P29466 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13532194 | 0.92 | KMT2A (0.85) | KMT2AHTTHSD17B10CASP1TP53 | |
| SCHEMBL13532184 | 0.90 | KMT2A (0.82) | KMT2AHTTHSD17B10CASP1TP53 | |
| SCHEMBL4250870 | 0.90 | KMT2A (0.81) | KMT2AHTTHSD17B10CASP1TP53 | |
| SCHEMBL7321050 | 0.89 | KMT2A (0.80) | KMT2AHTTHSD17B10CASP1ALDH1A1 | |
| SCHEMBL4247271 | 0.88 | KMT2A (0.78) | KMT2AHTTHSD17B10CASP1SMN1; SMN2 | |
| SCHEMBL31174712 | 0.87 | KMT2A (0.77) | KMT2AHTTHSD17B10CASP1SMN1; SMN2 | |
| SCHEMBL13532172 | 0.86 | KMT2A (0.76) | KMT2AHTTHSD17B10CASP1TP53 | |
| SCHEMBL13532208 | 0.86 | ALB (0.82) | KMT2ATP53POLBALDH1A1MEN1 | |
| SCHEMBL3491206 | 0.85 | TP53 (1.00) | KMT2AHSD17B10TP53POLBSMN1; SMN2 | |
| SCHEMBL6348773 | 0.84 | ALB (0.80) | KMT2ATP53ALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| WO-2008022171-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, NCEH1 | KMT2A 2861/4885HTT 2852/4885HSD17B10 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.