⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912351 | 0.91 | — | — | |
| SCHEMBL13532221 | 0.90 | — | — | |
| SCHEMBL14140990 | 0.84 | — | — | |
| SCHEMBL13392125 | 0.84 | — | — | |
| SCHEMBL10100148 | 0.83 | — | — | |
| SCHEMBL13532218 | 0.83 | — | — | |
| SCHEMBL13532213 | 0.82 | PIK3CD (0.34) | — | |
| SCHEMBL10100144 | 0.81 | CSNK2A2 (0.33) | — | |
| SCHEMBL12388999 | 0.81 | CSNK2A2 (0.32) | — | |
| SCHEMBL14943003 | 0.81 | CSNK2A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440813-B2 | Antiviral nucleoside analogs | BIOCRYST PHARMACEUTICALS, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| EP-2535345-A1 | Anticancer nucleoside analogs | BioCryst Pharmaceuticals, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20100015094-A1 | ANTIVIRAL NUCLEOSIDE ANALOGS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2010-01-21 | — | — | US | disclosed |