Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 16/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13534429 | 0.92 | SMO (0.64) | SMO | |
| SCHEMBL1836517 | 0.90 | SMO (0.76) | SMO | |
| SCHEMBL30090720 | 0.90 | SMO (0.76) | SMO | |
| SCHEMBL3206295 | 0.88 | SMO (0.84) | SMO | |
| SCHEMBL13445009 | 0.85 | SMO (0.74) | SMO | |
| SCHEMBL1836414 | 0.82 | SMO (0.57) | SMO | |
| SCHEMBL3212832 | 0.81 | SMO (0.84) | SMO | |
| SCHEMBL3595660 | 0.78 | SMO (0.75) | SMO | |
| Leq506 SCHEMBL29362923 | 0.78 | SMO (1.00) | SMO | |
| Leq506 SCHEMBL30090497 | 0.78 | SMO (1.00) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318389-B1 | PYRIDAZINE DERIVATIVES AS SMO INHIBITORS | NOVARTIS AG (CH) | 2013-06-19 | — | — | EP | disclosed |
| WO-2010007120-A1 | PYRIDAZINE DERIVATIVES AS SMO INHIBITORS | NOVARTIS AG (CH) | 2010-01-21 | — | — | WO | disclosed |