SCHEMBL13537659 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	PIM2	Q9P1W9	19/20	0.77

▸	PIM1	P11309	17/20	0.71

▸	PIM3	Q86V86	16/20	0.71

▸	STK17B	O94768	2/20	0.64

▸	BCL2	P10415	2/20	0.64

▸	CSNK2A2	P19784	2/20	0.64

▸	CDK7	P50613	2/20	0.64

▸	DAPK1	P53355	2/20	0.64

▸	CAMK4	Q16566	2/20	0.64

▸	MAPK15	Q8TD08	2/20	0.64

▸	PNPLA2	Q96AD5	2/20	0.64

▸	HIPK3	Q9H422	2/20	0.64

▸	KCNH2	Q12809	1/20	0.61

▸	TTR	P02766	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13537644	1.00	PIM2 (0.77)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL13537657	0.94	PIM2 (0.78)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL2425796	0.87	PIM2 (1.00)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL2425800	0.87	PIM2 (1.00)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL1580732	0.87	PIM2 (1.00)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL2425802	0.87	PIM2 (1.00)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL1581165	0.87	PIM2 (0.88)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL1578656	0.87	PIM2 (1.00)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL1581162	0.87	PIM2 (0.88)	PIM2PIM1PIM3STK17BBCL2
SCHEMBL1580735	0.87	PIM2 (1.00)	PIM2PIM1PIM3STK17BBCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010001169-A2	CHEMICAL COMPOUNDS 251	ASTRAZENECA AB (SE)	2010-01-07	—	—	WO	disclosed