Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.61 |
| ▸ | HSP90AB1 | P08238 | 19/20 | 0.61 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.47 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539714 | 0.89 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL13539625 | 0.88 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL13539632 | 0.84 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL13539741 | 0.82 | HSP90AB1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL12613418 | 0.80 | HSP90AA1 (0.84) | HSP90AA1HSP90AB1 | |
| SCHEMBL14471018 | 0.79 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL1056688 | 0.79 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL12614031 | 0.78 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL12613575 | 0.78 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL12614036 | 0.77 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145888-A1 | Deazapurine derivatives as HSP90-Inhibitors | Conforma Therapeutics Corporation (US) | 2010-01-20 | — | — | EP | disclosed |