Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | VHL | P40337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133623 | 0.82 | KMT2A (0.76) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL10202712 | 0.81 | KMT2A (0.59) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL885068 | 0.79 | KMT2A (0.66) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL20715705 | 0.79 | KMT2A (0.56) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL12646172 | 0.79 | KMT2A (0.56) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL20715716 | 0.78 | KMT2A (0.51) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL23627121 | 0.77 | KMT2A (0.54) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL5608007 | 0.77 | SLC7A5 (0.61) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL5608012 | 0.77 | SLC7A5 (0.61) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL26161772 | 0.77 | KMT2A (0.54) | KMT2AHDAC1HDAC6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652023-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-01-26 | — | — | US | disclosed |
| US-20070135467-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135467-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | KMT2A 2236/4885HDAC1 39/4885HDAC6 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.