Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.90 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.72 |
| ▸ | FLT1 | P17948 | 9/20 | 0.72 |
| ▸ | BCR | P11274 | 5/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548646 | 0.95 | ABL1 (1.00) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL5866762 | 0.89 | ABL1 (0.87) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3537439 | 0.89 | ABL1 (0.85) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3537611 | 0.88 | ABL1 (0.84) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3531965 | 0.86 | ABL1 (0.84) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3538437 | 0.85 | ABL1 (1.00) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3533705 | 0.84 | ABL1 (1.00) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3538261 | 0.84 | ABL1 (1.00) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3534446 | 0.84 | ABL1 (0.72) | ABL1FGFR1FLT1BCRKDR | |
| SCHEMBL3538117 | 0.84 | ABL1 (0.75) | ABL1FGFR1FLT1BCRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642278-B2 | Nitrogen compounds such as 3-(5-morpholin-4-yl-1H-benz-imidazol-2-yl)-1H-indazole and/or isomers, used as immunology modulators, antidiabetic agents, antiogenesis inhibitors or for prophylaxis of Alzheimer's disease | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642278-B2 | Nitrogen compounds such as 3-(5-morpholin-4-yl-1H-benz-imidazol-2-yl)-1H-indazole and/or isomers, used as immunology modulators, antidiabetic agents, antiogenesis inhibitors or for prophylaxis of Alzheimer's disease | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-01-05 | — | — | US | disclosed |