Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 13/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12123993 | 0.89 | BRAF (0.47) | BRAFIGF1RCAMK2DCSF1REGFR | |
| SCHEMBL12123839 | 0.79 | BRAF (0.46) | BRAFIGF1RCAMK2DCSF1REGFR | |
| SCHEMBL12120858 | 0.78 | BRAF (0.53) | BRAFIGF1RCAMK2DCSF1RWEE1 | |
| SCHEMBL12124052 | 0.78 | BRAF (0.45) | BRAFIGF1RCAMK2DCSF1REGFR | |
| SCHEMBL12671538 | 0.76 | BRAF (0.50) | BRAFIGF1RCAMK2DCSF1RWEE1 | |
| SCHEMBL16497192 | 0.72 | SLC2A1 (0.38) | BRAFCAMK2DCSF1REGFRITK | |
| SCHEMBL13534038 | 0.72 | SLC2A1 (0.38) | BRAFCAMK2DCSF1REGFRITK | |
| SCHEMBL1845366 | 0.72 | PDPK1 (0.47) | BRAFCAMK2DCSF1R | |
| SCHEMBL1845368 | 0.72 | PDPK1 (0.47) | BRAFCAMK2DCSF1R | |
| SCHEMBL16497499 | 0.71 | PDPK1 (0.39) | BRAFCAMK2DCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007116-A2 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | WO | disclosed |