Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.74 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550323 | 0.90 | FFAR1 (0.79) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL3520902 | 0.89 | FFAR1 (0.61) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL13118336 | 0.88 | FFAR1 (0.76) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL6104254 | 0.88 | FFAR1 (0.72) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL3555589 | 0.88 | FFAR1 (0.72) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL13318210 | 0.86 | FFAR1 (0.68) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL12020986 | 0.86 | FFAR1 (0.68) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL13550367 | 0.86 | FFAR1 (0.74) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL13140168 | 0.86 | FFAR1 (0.79) | FFAR1PPARDPPARAMRGPRX4PPARG | |
| SCHEMBL3520171 | 0.85 | FFAR1 (0.69) | FFAR1PPARDPPARAMRGPRX4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649110-B2 | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders | AMGEN INC. (US) | 2010-01-19 | — | — | US | disclosed |