Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591172 | 0.94 | TSHR (0.63) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL1535633 | 0.91 | GAA (0.61) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL14497517 | 0.90 | TSHR (0.59) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL19720351 | 0.89 | TSHR (0.58) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL20711670 | 0.88 | GAA (0.56) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL13474871 | 0.87 | TSHR (0.56) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL7533362 | 0.87 | TSHR (0.75) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL13474879 | 0.86 | TSHR (0.55) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL13554256 | 0.86 | GAA (0.53) | TSHRGAAHTTALDH1A1ESR1 | |
| SCHEMBL20821921 | 0.86 | GAA (0.50) | TSHRGAAHTTALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, FLNB | TSHR 4504/4885GAA 4098/4885HTT 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.