Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437152 | 0.82 | MAPT (0.60) | PTPN1HSP90AA1HSP90AB1CA12CA1 | |
| SCHEMBL9626577 | 0.82 | MAPT (0.60) | PTPN1HSP90AA1HSP90AB1CA12CA1 | |
| SCHEMBL11018113 | 0.82 | PTPN1 (0.56) | PTPN1HSP90AA1HSP90AB1CA12CA1 | |
| SCHEMBL661487 | 0.80 | CA12 (0.72) | HSP90AA1HSP90AB1CA12CA1CA2 | |
| Ethane SCHEMBL10824994 | 0.80 | CA12 (0.53) | PTPN1HSP90AA1HSP90AB1CA12CA1 | |
| SCHEMBL1353392 | 0.79 | KMT2A (0.51) | PTPN1HSP90AA1HSP90AB1CA12CA1 | |
| SCHEMBL1353425 | 0.78 | HSD17B2 (0.70) | PTPN1HSP90AA1HSP90AB1CA12CA1 | |
| SCHEMBL9464075 | 0.78 | CYP1A2 (0.54) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL21221617 | 0.77 | KDM4E (0.66) | HSP90AA1HSP90AB1CA12CA1CA2 | |
| SCHEMBL10931223 | 0.77 | PTPN1 (0.67) | PTPN1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280940-A1 | Di-Vanilloyl And Tri-Vanilloyl Derivatives For Use In Anti-Cancer Therapy | KISS ROBERT (BE) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280940-A1 | Di-Vanilloyl And Tri-Vanilloyl Derivatives For Use In Anti-Cancer Therapy | PSEN2, PSEN1, VHL | PTPN1 2575/4885HSP90AA1 2978/4885HSP90AB1 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.