Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13554330 | 0.93 | GAA (0.32) | GAAL3MBTL1HTT | |
| SCHEMBL13554370 | 0.91 | TSHR (0.31) | TSHRKMT2A | |
| SCHEMBL15672481 | 0.89 | GAA (0.41) | GAAL3MBTL1HTT | |
| SCHEMBL18948174 | 0.88 | — | — | |
| SCHEMBL4409167 | 0.85 | GAA (0.36) | GAAL3MBTL1HTT | |
| SCHEMBL13257025 | 0.83 | GAA (0.38) | GAAL3MBTL1HTT | |
| SCHEMBL18948234 | 0.82 | — | — | |
| SCHEMBL17350999 | 0.81 | — | — | |
| SCHEMBL16518712 | 0.81 | GAA (0.36) | GAAL3MBTL1HTT | |
| SCHEMBL15672512 | 0.81 | GAA (0.39) | GAAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, FLNB | GAA 4098/4885L3MBTL1 3018/4885HTT 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.