Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.52 |
| ▸ | PGR | P06401 | 14/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773112 | 0.83 | AR (0.48) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL10089125 | 0.81 | AR (0.55) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL16564526 | 0.79 | AR (0.46) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL4223212 | 0.78 | AR (0.52) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL12904908 | 0.78 | AR (0.65) | ARPGRNR3C2 | |
| SCHEMBL12904942 | 0.78 | AR (0.65) | ARPGRNR3C2 | |
| SCHEMBL12942706 | 0.78 | AR (0.55) | ARPGRNR3C2LMNANR3C1 | |
| SCHEMBL12942779 | 0.78 | AR (0.55) | ARPGRNR3C2LMNANR3C1 | |
| SCHEMBL13474770 | 0.78 | AR (0.50) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL12904977 | 0.78 | AR (0.65) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |