Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40911 | 0.96 | HDAC8 (0.42) | HDAC8NOS3NOS1NOS2PI4KA | |
| Hydrochloric Acid SCHEMBL1882279 | 0.96 | HDAC8 (0.42) | HDAC8NOS3NOS1NOS2PI4KA | |
| SCHEMBL1551556 | 0.96 | HDAC8 (0.42) | HDAC8NOS3NOS1NOS2PI4KA | |
| Iodide SCHEMBL28626956 | 0.93 | HDAC8 (0.41) | HDAC8NOS3NOS1NOS2PI4KA | |
| Ammonia Solution, Strong SCHEMBL11318385 | 0.93 | HDAC8 (0.41) | HDAC8NOS3NOS1NOS2PI4KA | |
| Hydrochloric Acid SCHEMBL2635755 | 0.93 | HDAC8 (0.41) | HDAC8NOS3NOS1NOS2PI4KA | |
| Hydrochloric Acid SCHEMBL2635245 | 0.91 | HDAC8 (0.39) | HDAC8NOS3NOS1NOS2PI4KA | |
| Iodide SCHEMBL5015539 | 0.91 | HDAC8 (0.39) | HDAC8NOS3NOS1NOS2PI4KA | |
| Hydrochloric Acid SCHEMBL11323291 | 0.91 | HDAC8 (0.39) | HDAC8NOS3NOS1NOS2PI4KA | |
| Perchlorate SCHEMBL11315497 | 0.86 | KDM4E (0.39) | HDAC8NOS3NOS1NOS2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111841644-B | Metal-organic complex immobilized phosphotungstic acid catalyst for synthesizing epoxy cyclohexane | 郑州大学 | 2022-10-28 | — | — | CN | claimed |
| CN-109696782-A | A kind of nano fibrous membrane base discoloration gel-type Electrochromic device and its preparation and application | 东华大学 | 2019-04-30 | — | — | CN | claimed |
| CN-109557740-A | A kind of preparation method of purple Luo Jingji flexible color changing piece | 东华大学 | 2019-04-02 | — | — | CN | claimed |
| CN-108873539-A | A kind of electrochromism fiber and its preparation and application | 东华大学 | 2018-11-23 | — | — | CN | claimed |
| US-4376569-A | Electrolyte for an electrochromic display | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1983-03-15 | — | — | US | claimed |
| EP-0019692-B1 | ELECTROLYTE FOR AN ELECTROCHROMIC DISPLAY AND AN ELECTROCHROMIC DISPLAY CELL COMPRISING THIS ELECTROLYTE | International Business Machines Corporation (US) | 1983-02-09 | — | — | EP | claimed |
| EP-0019692-A1 | Electrolyte for an electrochromic display and an electrochromic display cell comprising this electrolyte | International Business Machines Corporation (US) | 1980-12-10 | — | — | EP | claimed |
| US-4201566-A | PENETRATING THE TREE WITH A BIPYRIDYLIUM SALT | BROWN CLAUD L | 1980-05-06 | — | — | US | claimed |
| EP-4315482-A1 | HALOGEN COMPLEXING AGENTS BOUND TO THE CATHODE SURFACE IN A STATIC ZINC HALIDE BATTERY | EOS Energy Technology Holdings, LLC (US) | 2024-02-07 | — | — | EP | disclosed |
| US-11211607-B2 | Bipolar electrode comprising a loaded carbon felt | EOS ENERGY STORAGE LLC (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200388844-A1 | BIPOLAR ELECTRODE COMPRISING A LOADED CARBON FELT | CITIBANK, N.A., AS COLLATERAL AGENT | 2020-12-10 | — | — | US | disclosed |
| EP-2966684-B1 | ELECTRONIC ELEMENT | JAPAN SCIENCE & TECH AGENCY (JP) | 2020-10-14 | — | — | EP | disclosed |
| US-20200251745-A1 | CHAMBERED FRAME INSERT | EOS ENERGY STORAGE, LLC (US) | 2020-08-06 | — | — | US | disclosed |
| CN-110147020-A | A kind of wearable self energizing multicolour display device and its preparation and application | 东华大学 | 2019-08-20 | — | — | CN | disclosed |
| EP-0019692-A1 | Electrolyte for an electrochromic display and an electrochromic display cell comprising this electrolyte | International Business Machines Corporation (US) | 1980-12-10 | — | — | EP | disclosed |
| EP-0001912-B1 | ELECTROLYTE FOR ELECTROCHROMIC DISPLAY DEVICE | International Business Machines Corporation (US) | 1980-11-12 | — | — | EP | disclosed |
| US-4212518-A | ELECTROCHROMIC CELL | CANON KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |
| US-4205903-A | Writing/erasing technique for an electrochromic display cell | SHARP KABUSHIKI KAISHA (JP) | 1980-06-03 | — | — | US | disclosed |
| US-4187003-A | Electrolyte for electrochromic display device | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| EP-0001912-A1 | Electrolyte for electrochromic display device | International Business Machines Corporation (US) | 1979-05-16 | — | — | EP | disclosed |