Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.54 |
| ▸ | PGR | P06401 | 18/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12904830 | 0.88 | AR (0.67) | ARNR3C2PGR | |
| SCHEMBL13797343 | 0.88 | AR (0.67) | ARNR3C2PGR | |
| SCHEMBL12904958 | 0.88 | AR (0.67) | ARNR3C2PGR | |
| SCHEMBL12904873 | 0.88 | AR (0.67) | ARNR3C2PGR | |
| SCHEMBL13797041 | 0.88 | AR (0.54) | ARNR3C2PGR | |
| SCHEMBL12904942 | 0.82 | AR (0.65) | ARNR3C2PGR | |
| SCHEMBL12904797 | 0.82 | AR (0.65) | ARNR3C2PGR | |
| SCHEMBL12904908 | 0.82 | AR (0.65) | ARNR3C2PGR | |
| SCHEMBL12904977 | 0.82 | AR (0.65) | ARNR3C2PGR | |
| SCHEMBL12904982 | 0.82 | AR (0.65) | ARNR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238148-B1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |