Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.55 |
| ▸ | PGR | P06401 | 15/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13474795 | 0.89 | AR (0.57) | ARNR3C2PGRLMNASLC6A4 | |
| SCHEMBL12942849 | 0.80 | AR (0.57) | ARNR3C2PGR | |
| SCHEMBL13797573 | 0.80 | AR (0.54) | ARNR3C2PGRLMNASLC6A4 | |
| SCHEMBL12942781 | 0.80 | AR (0.57) | ARNR3C2PGR | |
| SCHEMBL12942739 | 0.80 | AR (0.57) | ARNR3C2PGR | |
| SCHEMBL13062189 | 0.79 | AR (0.67) | ARNR3C2PGRLMNASLC6A4 | |
| SCHEMBL13797681 | 0.77 | AR (0.40) | ARNR3C2PGRLMNASLC6A4 | |
| SCHEMBL12942706 | 0.73 | AR (0.55) | ARNR3C2PGRLMNANR3C1 | |
| SCHEMBL12942779 | 0.73 | AR (0.55) | ARNR3C2PGRLMNANR3C1 | |
| SCHEMBL12942714 | 0.73 | AR (0.55) | ARNR3C2PGRLMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238148-B1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |