Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 19/20 | 0.83 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364079 | 0.91 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4353457 | 0.89 | TNK2 (1.00) | TNK2 | |
| SCHEMBL13618361 | 0.89 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4353454 | 0.89 | TNK2 (1.00) | TNK2 | |
| SCHEMBL13626521 | 0.87 | TNK2 (0.82) | TNK2 | |
| SCHEMBL4364083 | 0.81 | TNK2 (0.67) | TNK2CSNK2A2CSNK2A1 | |
| SCHEMBL4362526 | 0.78 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4353507 | 0.78 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4368927 | 0.78 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4368467 | 0.77 | TNK2 (1.00) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283020-B1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARM INC (US) | 2012-10-31 | — | — | EP | disclosed |