Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL13517218 | 0.99 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRM3CHRM2CHRM1 | |
| SCHEMBL13563738 | 0.86 | NPSR1 (0.40) | CHRM3CHRM2CHRM1CNR2SLC6A9 | |
| Bromide SCHEMBL13517326 | 0.85 | NPSR1 (0.42) | CHRM3CHRM2CHRM1CNR2IDO1 | |
| SCHEMBL880903 | 0.84 | CHRM3 (0.53) | CHRNB4CHRNA3CHRM3CHRM2CHRM1 | |
| SCHEMBL230535 | 0.84 | CHRM3 (0.53) | CHRNB4CHRNA3CHRM3CHRM2CHRM1 | |
| SCHEMBL230536 | 0.84 | CHRM3 (0.53) | CHRNB4CHRNA3CHRM3CHRM2CHRM1 | |
| SCHEMBL13563746 | 0.84 | CHRM3 (0.34) | CHRM3CHRM2IDO1TDO2MEN1 | |
| Hydrochloric Acid SCHEMBL13735247 | 0.83 | CHRM3 (0.34) | CHRM3CHRM2IDO1TDO2MEN1 | |
| SCHEMBL13563745 | 0.82 | BCHE (0.38) | CHRM3CHRM2IDO1TDO2MEN1 | |
| SCHEMBL13563749 | 0.82 | KAT6A (0.37) | CHRM3CHRM2CHRM1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120276018-A1 | ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120276018-A1 | ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHRM3, BCHE, CHRM1 | CHRNB4 147/4885CHRNA3 48/4885CHRM3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.