Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090448 | 1.00 | NPY2R (0.41) | NPY2RKDM4ELMNACNR2GAA | |
| SCHEMBL17090181 | 1.00 | NPY2R (0.41) | NPY2RKDM4ELMNACNR2GAA | |
| SCHEMBL13565032 | 0.89 | KDM4E (0.37) | KDM4ELMNACNR2DRD2HTR2A | |
| SCHEMBL13565030 | 0.89 | USP30 (0.39) | KDM4ELMNACNR2 | |
| SCHEMBL11935386 | 0.88 | NPY5R (0.40) | NPY2RKDM4ELMNA | |
| SCHEMBL13439095 | 0.88 | NPY5R (0.40) | NPY2RKDM4ELMNA | |
| SCHEMBL11941125 | 0.88 | NPY5R (0.40) | NPY2RKDM4ELMNA | |
| SCHEMBL13564738 | 0.84 | MAPT (0.43) | CNR2HTR2ADRD3 | |
| SCHEMBL11936149 | 0.84 | MAPT (0.43) | CNR2HTR2ADRD3 | |
| SCHEMBL13565140 | 0.84 | MAPT (0.43) | CNR2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |