Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090028 | 1.00 | BRD4 (0.34) | BRD4NPY5RGRIA2PTGER4 | |
| SCHEMBL13565472 | 0.80 | GRIA2 (0.35) | NPY5RGRIA2 | |
| SCHEMBL10114902 | 0.80 | ABL1 (0.39) | BRD4GRIA2 | |
| SCHEMBL14424374 | 0.80 | ABL1 (0.39) | BRD4GRIA2 | |
| SCHEMBL11935443 | 0.78 | PTGER4 (0.39) | PTGER4 | |
| SCHEMBL13439175 | 0.78 | PTGER4 (0.39) | PTGER4 | |
| SCHEMBL17090026 | 0.77 | GRIA2 (0.36) | NPY5RGRIA2 | |
| SCHEMBL13565316 | 0.77 | GRIA2 (0.36) | NPY5RGRIA2 | |
| SCHEMBL17090190 | 0.77 | PTGER4 (0.35) | BRD4NPY5RGRIA2PTGER4 | |
| SCHEMBL13565307 | 0.77 | PTGER4 (0.35) | BRD4NPY5RGRIA2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |