Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567265 | 1.00 | ESR1 (0.57) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL14586721 | 1.00 | ESR1 (0.57) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL28351781 | 0.98 | ESR1 (0.54) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL28352143 | 0.98 | ESR1 (0.58) | ESR1ESR2MMP3BCL2L1SENP1 | |
| SCHEMBL5530423 | 0.91 | APP (0.50) | ESR1ESR2APPCA12CA1 | |
| SCHEMBL4851039 | 0.91 | APP (0.50) | ESR1ESR2APPCA12CA1 | |
| SCHEMBL13567210 | 0.91 | APP (0.50) | ESR1ESR2APPCA12CA1 | |
| SCHEMBL6670459 | 0.91 | APP (0.50) | ESR1ESR2APPCA12CA1 | |
| SCHEMBL5525269 | 0.89 | APP (0.52) | ESR1ESR2APPCA12CA1 | |
| SCHEMBL22127728 | 0.87 | ESR1 (0.65) | ESR1ESR2MMP3BCL2L1SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |