Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MITF | O75030 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MGAM | O43451 | 2/20 | 0.62 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283294 | 0.89 | KMT2A (0.67) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL13568969 | 0.89 | MGAM (0.68) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL19283295 | 0.89 | KMT2A (0.67) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL13568916 | 0.89 | NPC1 (0.66) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL12218238 | 0.88 | MIF (0.65) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL685220 | 0.87 | KDM1A (0.67) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL683806 | 0.86 | GAA (0.65) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL13568891 | 0.85 | KMT2A (0.66) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL12937866 | 0.85 | MGAM (0.69) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL13569089 | 0.84 | MGAM (0.62) | MAPTKMT2APOLBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |