Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364231 | 0.82 | SMN1; SMN2 (0.46) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL23200000 | 0.77 | USP2 (0.47) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL19524673 | 0.76 | CHRM2 (0.38) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL19524660 | 0.76 | CHRM2 (0.38) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL13280416 | 0.73 | CHRM2 (0.46) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL23200029 | 0.73 | USP2 (0.51) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL19524675 | 0.73 | CHRM2 (0.38) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL13538376 | 0.68 | — | — | |
| SCHEMBL13538266 | 0.63 | TACR1 (0.41) | KDM4E | |
| SCHEMBL10061630 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153457-A2 | NOVEL COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2009-12-23 | — | — | WO | disclosed |