Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 5/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276888 | 0.91 | KCNH2 (0.56) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL4273390 | 0.86 | KCNH2 (0.63) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL20056101 | 0.83 | CACNA1I (0.49) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL19112926 | 0.82 | CACNA1I (0.56) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL4276850 | 0.79 | CACNA1I (0.61) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL13569697 | 0.78 | KCNH2 (0.45) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL19112577 | 0.78 | KCNH2 (0.49) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL13569753 | 0.77 | KCNH2 (0.47) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 | |
| SCHEMBL13569812 | 0.77 | KCNH2 (0.55) | KCNH2CACNA1ICACNA1GCACNA1HKMT2A | |
| SCHEMBL4284353 | 0.76 | CACNA1I (0.61) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |