Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229186 | 0.92 | HDAC1 (0.46) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13570023 | 0.89 | HDAC1 (0.45) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13569891 | 0.89 | HDAC1 (0.43) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13569963 | 0.86 | HDAC1 (0.43) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13569889 | 0.86 | HDAC1 (0.43) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13569960 | 0.86 | HDAC3 (0.45) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL4224169 | 0.85 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13570022 | 0.85 | HDAC3 (0.41) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL13570003 | 0.84 | HDAC1 (0.49) | HDAC1HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL13569962 | 0.83 | HDAC1 (0.45) | HDAC1HDAC3HDAC2HDAC8HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |