Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.65 |
| ▸ | CACNA1I | Q9P0X4 | 11/20 | 0.65 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283962 | 0.91 | CACNA1I (0.69) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL13569928 | 0.88 | KCNH2 (0.62) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL8374246 | 0.84 | CACNA1I (0.60) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL19112561 | 0.83 | CACNA1I (0.69) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL4283935 | 0.82 | CACNA1I (0.69) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL13569695 | 0.82 | KCNH2 (0.62) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL1427923 | 0.82 | KCNH2 (0.70) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL13569687 | 0.81 | KCNH2 (0.60) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL4273580 | 0.81 | CACNA1I (0.66) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 | |
| SCHEMBL4280373 | 0.81 | CACNA1I (0.72) | KCNH2CACNA1ICACNA1HCACNA1GMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |