Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96778 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL96686 | 0.82 | CHRM2 (0.55) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL9289352 | 0.82 | CHRM2 (0.55) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL16386083 | 0.79 | CHRM2 (0.36) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL96440 | 0.79 | CHRM2 (0.36) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL15444947 | 0.79 | CHRM2 (0.36) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL96789 | 0.77 | CHRM2 (0.37) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL15170714 | 0.71 | — | — | |
| SCHEMBL173191 | 0.71 | — | — | |
| SCHEMBL9252033 | 0.70 | CYP2D6 (0.48) | CHRM2CHRM1MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632836-B2 | Dialkylamino alkyl esters of pivagabine as medicaments for the treatment of central nervous system disorders | CENERX BIOPHARMA, INC. (US) | 2009-12-15 | — | — | US | disclosed |