Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.98 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | SCNN1A | P37088 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1428047 | 0.99 | KCNH2 (0.98) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11959362 | 0.99 | KCNH2 (1.00) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| Bromide SCHEMBL1428944 | 0.98 | KCNH2 (1.00) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11959350 | 0.97 | KCNH2 (0.95) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| Bromide SCHEMBL1428373 | 0.96 | KCNH2 (0.95) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11959332 | 0.95 | KCNH2 (0.92) | KCNH2CHRM4SCNN1AKDM4ENPC1 | |
| SCHEMBL13573266 | 0.93 | KCNH2 (0.85) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11959364 | 0.92 | KCNH2 (0.87) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13573304 | 0.92 | KCNH2 (0.82) | KCNH2SCNN1AKDM4ENPC1ALDH1A1 | |
| SCHEMBL11959374 | 0.91 | KCNH2 (0.84) | KCNH2SCNN1AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150137-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-17 | — | — | WO | disclosed |