Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 12/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 12/20 | 0.48 |
| ▸ | BIRC3 | Q13489 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13574334 | 0.97 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL26267832 | 0.97 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL13574410 | 0.84 | XIAP (0.44) | XIAPBIRC2BIRC3 | |
| SCHEMBL13574453 | 0.84 | XIAP (0.44) | XIAPBIRC2BIRC3 | |
| SCHEMBL2439908 | 0.84 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL12300017 | 0.84 | XIAP (0.49) | XIAPBIRC2BIRC3 | |
| SCHEMBL11928050 | 0.83 | XIAP (0.45) | XIAPBIRC2BIRC3 | |
| SCHEMBL13574430 | 0.83 | XIAP (0.54) | XIAPBIRC2BIRC3 | |
| SCHEMBL15093340 | 0.82 | BIRC2 (0.53) | XIAPBIRC2BIRC3 | |
| SCHEMBL15065057 | 0.82 | BIRC2 (0.53) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155709-A1 | BRIDGED SECONDARY AMINES AND USE THEREOF AS IAP BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2009-12-30 | — | — | WO | disclosed |