Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845746 | 0.84 | CYP2C9 (0.53) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL710842 | 0.84 | CYP2C9 (0.53) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL12845745 | 0.83 | CYP2C19 (0.51) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL28383608 | 0.83 | CHEK2 (0.58) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL16421721 | 0.83 | CYP2C9 (0.51) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL13574603 | 0.82 | PDGFRB (0.48) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL451366 | 0.81 | CYP2C19 (0.50) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL19340032 | 0.81 | CYP2C9 (0.50) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL5320922 | 0.81 | CYP2C9 (0.50) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 | |
| SCHEMBL1505679 | 0.81 | CYP2C9 (0.50) | CYP2C9CYP2C19LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150381-A2 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2009-12-17 | — | — | WO | disclosed |