Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 17/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 3/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612537 | 1.00 | MAP3K14 (0.46) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL12714912 | 1.00 | MAP3K14 (0.46) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL1612535 | 0.93 | MAP3K14 (0.47) | MAP3K14MAP4K4PAK4 | |
| SCHEMBL1614086 | 0.90 | MAP3K14 (0.48) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL1614647 | 0.90 | MAP3K14 (0.48) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL1612639 | 0.90 | MAP3K14 (0.48) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL12714856 | 0.90 | MAP3K14 (0.48) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL12714847 | 0.88 | MAP3K14 (0.47) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL1612136 | 0.88 | MAP3K14 (0.47) | MAP3K14MAP4K4PAK4PRKD1 | |
| SCHEMBL1613474 | 0.88 | MAP3K14 (0.47) | MAP3K14MAP4K4PAK4PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |